Shailee S. Shah, MD

Oncologists explore the challenges of distinguishing between chemotherapy fatigue and cancer-related limb pain, emphasizing the need for effective screening tools.

Experts discuss diagnosing Lambert-Eaton Myasthenic Syndrome, emphasizing clinical features, serologic tests, and the importance of neurologist involvement.

Shailee S. Shah, MD, details current screening and diagnostic guidelines for small cell lung cancer–associated LEMS.

Oncologists and neurologists enhance patient care through effective collaboration, early screening, and utilizing specialized resources for cancer-associated conditions.

Oncologists explore updated NCCN guidelines for diagnosing neurologic paraneoplastic syndromes in small cell lung cancer, emphasizing multidisciplinary care.

Explore effective treatment monitoring strategies for amifampridine, including side effects management and titration techniques for optimal patient care.

Oncologists explore the challenges of distinguishing between chemotherapy fatigue and cancer-related limb pain, emphasizing the need for effective screening tools.

Panelists discuss how CA-LEMS biology reflects an off-target antitumor immune response (often with SCLC) that generates antibodies against presynaptic VGCCs, reducing acetylcholine release and causing proximal weakness with brief strength improvement after repeated activation.

Panelists discuss how early segment-level recognition of CA-LEMS hinges on spotting hallmark clinical cues (proximal lower-extremity weakness, autonomic dysfunction, and reflexes that transiently improve after exercise) and not dismissing symptoms as deconditioning or cancer-treatment effects, given frequent links to SCLC and other malignancies.

Drs Sands and Shah discuss LEMS symptom identification and what guidelines currently note as best practices for the diagnosis of this disease.

Dr Shah discusses a study of the effect of immune checkpoint inhibitors on patients with cancer and preexisting neurologic autoimmune diseases.

Shailee S. Shah, MD, shares data on the frequency and severity of NAID exacerbation with ICIs in patients with cancer.