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Extended Follow-up Analysis of First-Line Treatment for Metastatic Gastric Cancer, Gastroesophageal Junction Cancer and Esophageal Adenocarcinoma

New Trial Tests Chemotherapy Regimen Following Pancreatic Cancer Surgery

A new clinical trial is testing the effectiveness of chemotherapy treatment following surgery for a subset of pancreatic cancer patients.

Patient Experiences Can Affect a Practice’s Financial Health

The patient experience is a critical factor in the success of any healthcare practice, and its importance is increasing with the rise of health care consumerism.

Bispecific Targeting CD3 and BCMA Reflect Expanding Options in Multiple Myeloma

Bispecific antibodies targeting BCMA have shown efficacy in relapsed refractory multiple myeloma, including bispecifics targeting BCMA x CD3.

Percutaneous Hepatic Perfusion Could Boost Immunotherapy Response in Metastatic Melanoma

Disrupting liver-driven immune sink by depleting macrophages and preventing T-cell clearance restores responsiveness to immunotherapy in melanoma.

Comprehensive Treatment Advances Care for Patients With Early-Stage Breast Cancer

Advances in the diagnosis and treatment of early-stage breast cancer highlight the need for clinicians to adapt to paradigm shifts that will have notable effects on patient care.

Palliative Care Builds Bridges in Oncology Practice

Toby Campbell, MD, MSCI, discusses the nuances of palliative care in oncology.

The Microbiome and Colon Cancer: Dietary Influence on Incidence, Morbidity, and Mortality

One of the prime risk factors for CRC is the consumption of a high-risk, Western-style diet high in processed foods, refined grains, red meat, and sugar.

Cemiplimab monotherapy for first-line advanced NSCLC patients with PD-L1 expression ≥50%: 6-y outcomes of EMPOWER-Lung 1

Rapid readout: Real-world lifileucel TIL shows 44% responses in metastatic melanoma, favoring early referral and manageable IL-2 toxicity.

Evidence Supports Value of Physical Activity in Patients With Cancer

Baseline physical activity and physical function prior to a cancer diagnosis or treatment affects survival, with evidence spanning across solid tumor types and hematologic malignancies.

Ongoing Research to Watch in EGFR-Mutated NSCLC

Natalie Vokes, MD, and Sid Devarakonda, MBBS, MD, discuss ongoing research shaping EGFR-mutated NSCLC care.

INCB123667 Advances to Phase 3 Following Encouraging Activity in Platinum-Resistant Ovarian Cancer

Premal H. Thaker, MD, MS, discusses INCB123667 in ovarian cancer and the ongoing MAESTRA 2 study.

Building Upon Scaffolds

Cancer care is changing rapidly, and understanding and incorporating new practices is challenging both for practicing oncologists and oncology trainees.

How Genetic Information Keeps Cells Alive: A New Model from Moffitt Cancer Center

A new model explains how genetic information is not just stored but continuously used to keep cells organized and functioning.

Data Quality Issues Plague the US Health Care System

Oleg Bess, MD, explains why data quality is essential to improving the United States health care system.

Roginolisib Demonstrates Preliminary Activity in Metastatic Uveal Melanoma

Phase 1 data support continued investigation of roginolisib in advanced cancers, including metastatic uveal melanoma.

Novel Detection Methods May End Chemotherapy for Patients With CRC

A new genetic test that may allow patients with colorectal cancer to avoid chemotherapy after tumor resection is under investigation at AdventHealth Cancer Institute in Orlando, Florida.

Ohio State Recruits Top Oncologist to Expand Cell Therapy Program, Lead Bone Marrow Transplant Services

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has recruited Marcos J. de Lima, MD, to lead its Blood and Marrow Transplant and Cellular Therapy programs, two key leadership positions within central Ohio’s only National Cancer Institute-designated comprehensive cancer center and largest freestanding hospital.

UCSF Prostate Cancer Program Awarded SPORE Grant by National Cancer Institute

Researchers will investigate aggressive prostate cancer from a mechanistic, biomarker and therapeutic perspective.

Direct Partnership With Patients May Accelerate Cancer Research and Precision Oncology

During the past several decades, cancer research has produced revolutionary discoveries leading to dramatic results for many patients.

Clinical Updates for the Management of Lung Cancer Brain Metastases

As improved cancer therapies are helping patients live longer, the safe and effective management of lung cancer brain metastases is coming to the fore.

Physicians Must Become Advocates to Play a Role in Community Oncology’s Future

Although some community oncologists may think they can do little to abate the reimbursement reform forces that are affecting their practices, there are actions they can, and should, take to influence the success of their value-based care journey that may not be part of the fundamentals of their current practice.

Multi-stakeholder collaboration: the catalyst for innovation in kidney cancer care

Sponsored Content by Ipsen

Study Reveals Distinct Cellular and Genetic Differences in Colorectal Cancer in Younger Patients

Dana-Farber, Mass General Brigham, and Broad Institute researchers uncovered clues to why colorectal cancer can be more aggressive in younger people.

Gemcitabine Intravesical System Yields Low Rate of Radical Cystectomy in BCG-Unresponsive, High-Risk NMIBC

Gemcitabine intravesical system in BCG-unresponsive, high-risk NMIBC led to high CR rates and low radical cystectomy rates.

Why Oncologists Should Know More About Medical Marijuana

Increasingly, patients are asking oncologists for guidance and recommendations for the use of medical marijuana. However, finding those answers is challenging because of the federal government.