Patient Tragedy Inspires Program Focused on Immune-Related Toxicities

Jason Harris
Published: Wednesday, Jan 08, 2020
Kerry L.
Reynolds, MD

Kerry L. Reynolds, MD

The advent of immunotherapy options to treat patients with cancer has brought with it a new wave of immuno-related toxicities. One institution, Massachusetts General Hospital (MGH), has taken steps to establish an immunotherapy toxicity service care team, inspired by a 65-year-old patient with metastatic melanoma that had spread to his lungs and brain. David M.’s case posed many questions, including the best ways to prepare to manage and possibly predict these adverse events.

Members meet on a biweekly case conference call to review each incidence of toxicity. They discuss each patient and the relevant literature and look for gaps in their knowledge. Then, to fill those gaps, they can refer to a registry of patients treated at the hospital with immune checkpoint inhibitors.

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