Unraveling Neuroendocrine Tumors: Clinician Reflects on 60 Years of Discovery

Richard R.P. Warner, MD
Published: Wednesday, Mar 01, 2017
Richard R.P. Warner, MD

Richard R.P. Warner, MD

At age 89, I could probably earn the Guinness World Record for the oldest neuroendocrine cancer clinician in the United States, and perhaps even the world. I retired from clinical practice at The Mount Sinai Hospital in New York City in November 2016 to focus on research, lecturing, and patient advocacy. At this interesting point in my career, I am taking time to reflect on the more than 60 years I’ve spent studying, diagnosing, and treating patients with neuroendocrine tumors and carcinoid syndrome. I think it would be valuable to share the key learnings and insights that have built my legacy within this important field.

The Early Years: Piecing Together Evidence

During my internal medicine internship and residency in the early 1950s, a subspecialty in oncology was not yet recognized by a certifying board. Therefore, despite my interest in the eld, I chose to pursue a gastroenterology fellowship in 1954 and read everything in the literature that had any bearing on gastroenterology. I was impressed by an article in the American Heart Journal that mentioned a new syndrome marked by diarrhea and facial flushing, which was associated with little tumors (carcinoids) in the small intestine that had spread to the liver and with prominent right-sided heart valve lesions. This became known as "carcinoid syndrome."
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Online CME Activities
TitleExpiration DateCME Credits
Oncology Briefings™: Individualizing Treatment After Second-Line Therapy for Patients With mCRCAug 29, 20191.0
Community Practice Connections™: Immunotherapeutic Strategies with the Potential to Transform Treatment for Genitourinary CancersAug 29, 20191.0
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