August 2013 | OncologyLive

Gynecologic Cancers Symposium Puts Emphasis on Unsettled Questions

September 27, 2013

Hot topics, emerging therapies, and tough cases from the front lines of patient care will be featured during the 9th Annual International Symposium on Ovarian Cancer and Gynecologic Malignancies, scheduled for October 5 in Philadelphia.

Research Team in Canada Explores PARP's Complex Role in DNA Repair

September 09, 2013

Recently, Girish M. Shah's team has been using cellular and murine models to examine various therapeutic options, including inhibitor and gene knockout approaches against the DNA damage-responsive enzyme poly(ADP-ribose) polymerase 1 (PARP-1).

Rugo Offers Window Into Evolving Views of ER-Positive Disease

September 06, 2013

Research efforts are under way to improve the efficacy of hormone therapy in the management of advanced estrogen receptor-positive (ER) breast cancer, including new strategies for targeting the PI3K/ mTOR pathway.

Novel Drug Studies Yield Biomarker Candidates for Prostate Cancer Bone Turnover

September 04, 2013

Prostate cancer has a propensity to metastasize to bone. High turnover ultimately results in a net loss of bone tissue; prostate cancer treatment contributes to the loss of bone integrity, as androgen- deprivation therapy often causes abnormally low bone density

TNBC Studies Yield Clues for Future Directions

August 27, 2013

Researchers are still at the drawing board when it comes to finding revolutionary solutions for the treatment of triple-negative breast cancer, but studies have shed light on the diversity of the disease and offered hints about the directions future inquiries should take.