Articles

Although many labs study cancer as an all-or-nothing process, putting all metastable hybrid stages in the same bin, our laboratory at the University of Kentucky is exploring carcinogenesis as a continuum, from initiation through progression to maintenance. This approach has prompted us to focus on the role of epigenetics in cancer development.

University of Kentucky Lab Seeks to Decode Epigenetic Signals in Cancer

Lowell B. Anthony, MD, FACP, sheds light on important data that have shaped the current neuroendocrine tumors treatment paradigm and highlights notable ongoing studies.

NETs Treatment Arsenal Expands, With More Progress on the Horizon

Open access to unbiased data repositories of molecular and clinical data will be essential to accelerating future discoveries in precision medicine.

Kentucky Taps Into Data Repositories for an Attack on its Extraordinary Cancer Burden

Anthracyclines widely used for a variety of malignancies cause cardiotoxic effects that manifest as cardiomyopathy. Maya E. Guglin, MD, PhD, discusses supportive therapy for these patients.

Preventing Chemotherapy-Induced Cardiomyopathy: Can We? Should We?

The natural products produced
by microbes found in the environment have
led to major therapeutic breakthroughs for a variety
of conditions ranging from infectious disease
to cancer.  

Searching Appalachia for Next Great Cancer Drug

Videos

John A. D'Orazio, MD, PhD, associate professor, Department of Pediatrics, College of Medicine, University of Kentucky Markey Cancer Center, discusses ongoing research exploring ultraviolet radiation signature mutations in patients with melanoma.

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