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Opinion|Videos|August 2, 2024

1L treatment of lower-risk MDS beyond luspatercept

Author(s)Guillermo Garcia-Manero, MD, Rami Komrokji, MD, Esther Natalie Oliva, MD

Medical experts explore alternative treatment options for lower-risk myelodysplastic syndrome (LR-MDS) patients who are not suitable candidates for first-line luspatercept therapy.

Episodes in this series

5 KOLs are featured in this program

EP. 1 Navigating Myelodysplastic Syndromes: Updates to WHO & ICC Guidelines, IPSS-M, and Risk Stratification

5 KOLs are featured in this program

EP. 2 Dr Oliva on Addressing Challenges in Treating Lower-Risk MDS 

5 KOLs are featured in this program

EP. 3 Frontline Therapy for Lower-Risk MDS: Global Perspectives and Treatment Selection Strategies

5 KOLs are featured in this program

EP. 4 Review of the COMMANDS Trial

5 KOLs are featured in this program

EP. 5 Perceptions of the EHA 2024 Full Analysis of the COMMANDs Trial

5 KOLs are featured in this program

EP. 6 Clinical Implications of COMMANDS Trial in Clinical Practice

5 KOLs are featured in this program

EP. 7 Treatment Decision-Making Based on the COMMANDS Trials

5 KOLs are featured in this program

EP. 8 Exploring Biomarker Analysis, Real-World Data, and Quality of Life in LR-MDS: Insights from EHA 2024

5 KOLs are featured in this program

EP. 9 Dr.'s Cluzeau and Komrokji on Utilization Patterns of luspatercept in LR-MDS EHA 2024 Data

5 KOLs are featured in this program

EP. 10 Safety Profile of Available Frontline Treatments LR-MDS

5 KOLs are featured in this program

EP. 11 1L treatment of lower-risk MDS beyond luspatercept

5 KOLs are featured in this program

EP. 12 Sequencing Second-Line Treatments for LR-MDS

5 KOLs are featured in this program

EP. 13 Perspectives of IMerge Study

5 KOLs are featured in this program

EP. 14 Real-World Evidence and Emerging Therapies in Lower-Risk MDS: Insights from EHA 2024

5 KOLs are featured in this program

EP. 15 EHA 2024 Future Directions in Lower-Risk MDS Treatment: Emerging Data, Approvals, and Guideline Updates

5 KOLs are featured in this program

EP. 16 Final Thoughts on EHA 2024 Data for Lower-Risk MDS

For patients who are not suitable to receive 1L luspatercept for LR-MDS, what alternate treatment options would you consider?
What other trials on the horizon are you excited for in the 1L treatment of lower-risk MDS?

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