Feature|Articles|January 30, 2026

2025 Data Across Gynecologic, Lung, and Hematologic Cancers Reshape Treatment Landscapes

Author(s)Kyle Doherty
Fact checked by: Chris Ryan

OncLive spoke to 4 experts in order to unpack the top data presented during oncology conferences over the course of 2025.

Over the course of 2025, clinical trial data presented during major medical meetings across lung and gynecologic cancers, as well as hematologic malignancies, made major waves. Notable advances included the emergence of relacorilant (CORT125134) in platinum-resistant ovarian cancer (PROC), the confirmation of the role of tarlatamab-dlle (Imdelltra) in extensive-stage small cell lung cancer (ES-SCLC), and event-free survival (EFS) improvement with venetoclax (Venclexta) plus a hypomethylating agent (HMA) in induction-eligible acute myeloid leukemia (AML).

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