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Opinion|Videos|December 18, 2024

Brief Overview of Frontline Maintenance Therapy for Advanced Ovarian Cancer

Author(s)Thomas J. Herzog, MD, John Chan, MD

Panelists discuss how frontline maintenance therapy options for advanced ovarian cancer are influenced by key factors, such as a patient’s HRD status, and when a combination approach with PARP inhibitors and bevacizumab might be preferred over monotherapy.

Episodes in this series

EP. 1 Biomarker Testing in Advanced Ovarian Cancer

EP. 1 Biomarker Testing in Advanced Ovarian Cancer

EP. 2 Role of Genomic Instability Scores in Treatment Selection

EP. 2 Role of Genomic Instability Scores in Treatment Selection

EP. 3 Brief Overview of Frontline Maintenance Therapy for Advanced Ovarian Cancer

EP. 3 Brief Overview of Frontline Maintenance Therapy for Advanced Ovarian Cancer

EP. 4 Optimizing PARP Inhibitor Duration

EP. 4 Optimizing PARP Inhibitor Duration

EP. 5 Overview of PRIMA - Niraparib 1L Maintenance

EP. 5 Overview of PRIMA - Niraparib 1L Maintenance

EP. 6 Emerging Maintenance Strategies in Advanced/Metastatic Disease: Insights on Combination Therapies and Overcoming PARP Inhibitor Resistance

EP. 6 Emerging Maintenance Strategies in Advanced/Metastatic Disease: Insights on Combination Therapies and Overcoming PARP Inhibitor Resistance

EP. 7 Adverse Event Management and Emerging Therapies in Ovarian Cancer: PARPi Challenges and the Role of ADCs

EP. 7 Adverse Event Management and Emerging Therapies in Ovarian Cancer: PARPi Challenges and the Role of ADCs

Video content above is prompted by the following:

Dr Chan to ask Dr Herzog: Briefly review frontline maintenance therapy options for advanced ovarian cancer and highlight the key factors that guide your choice between available therapies.

How does a patient’s HRD status influence your selection of maintenance therapy?
Under what circumstances would you consider a combination approach with PARP inhibitors and bevacizumab vs using monotherapy?

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