Opinion|Videos|January 8, 2025
Emerging Maintenance Strategies in Advanced/Metastatic Disease: Insights on Combination Therapies and Overcoming PARP Inhibitor Resistance
Author(s)Thomas J. Herzog, MD, John Chan, MD
Panelists discuss PARP inhibitor resistance in ovarian cancer and explore strategies to overcome this challenge, including findings from the PRESERVE-004 trial evaluating gotistobart plus pembrolizumab, along with other potential treatment options. Additionally, they review insights from the SOPRANO trial regarding the management of oligometastases or oligoprogression in ovarian cancer.
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Episodes in this series
Video content above is prompted by the following:
- Dr Chan to ask Dr Herzog: Please comment on PARP inhibitor resistance. Are there promising strategies to overcome this challenge?
- PRESERVE-004: gotistobart plus pembrolizumab (
Barlin JN, et al. ESMO 2024. LBA32 ) - Others?
Dr Herzog to ask Dr Chan: What insights can be drawn from the SOPRANO trial findings regarding the management of oligometastases or oligoprogression in ovarian cancer? (
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