
Opinion|Videos|January 2, 2025
CDK4/6 Inhibitors for HR+/HER2- Early Breast Cancer
Panelists discuss how adjuvant therapy in HR+/HER2- early-stage breast cancer is influenced by key risk factors, with a focus on recent studies involving CDK4/6 inhibitors like abemaciclib, ribociclib, and palbociclib, and how these treatments are shaping the adjuvant treatment strategy based on efficacy data from trials such as MonarchE, NATALEE, and PALLAS.
Advertisement
Episodes in this series

Video content above is prompted by the following:
- How do you use adjuvant therapy in patients with HR+/HER2- early-stage breast cancer (eBC)?
- How do risk factors impact your adjuvant treatment strategy?
- Which risk factors are most influential, and why?
- Please briefly mention adjuvant CDK4/6i studies in eBC
Advertisement
Related to this article

The liquid biopsy identifies ESR1 mutations in blood to select patients with metastatic breast cancer who may be eligible for treatment with camizestrant.

Did you catch all of this week's top oncology news? Test your knowledge with OncLive's Weekly News Quiz.

China's approval of Dato-DXd for TNBC was supported by TROPION-Breast02 data showing a median OS of 23.7 months vs 18.7 months with chemotherapy.

Check out this September recap of OncLive’s coverage of the top news and expert insights in breast cancer.

Here is your cheat sheet to all therapeutic options that were cleared by the FDA in September 2026 spanning tumor types.

The FDA approved tucatinib plus trastuzumab and pertuzumab as maintenance for advanced HER2-positive breast cancer after induction.
Advertisement
Advertisement
Trending on OncLive
1
FDA Approves Tucatinib Plus Trastuzumab/Pertuzumab as First-Line Maintenance in Advanced HER2+ Breast Cancer
2
VIR-5500 Receives FDA Fast Track Designation in mCRPC
3
Iberdomide Plus Daratumumab/Dexamethasone Yields Significant PFS Benefit in R/R Myeloma
4
FDA Approves Atezolizumab Plus Chemo for Stage III dMMR Colon Cancer
5


