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Opinion|Videos|September 6, 2024

Clinical Insights: Looking Forward for pLGG

Author(s)Jason Fangusaro, MD

The leaders in the pediatric low-grade glioma (pLGG) field offer their concluding insights and perspectives on the future of pLGG management.

Episodes in this series

3 KOLs are featured in this series.

EP. 1 Overview of pLGG presentation and categorization

3 KOLs are featured in this series.

EP. 2 Molecular Characterization of pLGG

3 KOLs are featured in this series.

EP. 3 Less Common Molecular Alterations in pLGG and Testing Recommendations

3 KOLs are featured in this series.

EP. 4 Standard of care for frontline treatment of non-V600E-specific pLGG tumors

3 KOLs are featured in this series.

EP. 5 Ongoing clinical trials for frontline treatment of non-V600E-specific pLGG tumors

3 KOLs are featured in this series.

EP. 6 Current Treatment of Patients with NF1 pLGG

3 KOLs are featured in this series.

EP. 7 Standard of Care Pptions Specific for Frontline Treatment of BRAF V600E-Mutated pLGG

3 KOLs are featured in this series.

EP. 8 Treatment Considerations for Progressive pLGG

3 KOLs are featured in this series.

EP. 9 Radiation and Targeted Therapies for Progressive pLGG

3 KOLs are featured in this series.

EP. 10 The Role of Tovorafenib in Treatment of Progressive pLGG

3 KOLs are featured in this series.

EP. 11 Clinical Trials to Increase Treatment Options in the Progressive Setting

3 KOLs are featured in this series.

EP. 12 Clinical scenario 1 - BRAFKIAA-1549 fusion

3 KOLs are featured in this series.

EP. 13 Alternatives and Considerations for Clinical Scenario 1

3 KOLs are featured in this series.

EP. 14 Clinical Scenario 2 - BRAFV600E

3 KOLs are featured in this series.

EP. 15 Potential Adverse Events With Targeted Therapies

3 KOLs are featured in this series.

EP. 16 Clinical Insights: Looking Forward for pLGG

How do you approach long-term treatment planning and sequencing decisions as patients progress?
1. How do you incorporate radiotherapy into treatment sequencing?
2. When might treatment switching be appropriate?

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