Opinion|Videos|January 30, 2025
Clinical Trials and Real-World Data on Brexu-Cel
Panelists discuss how the dosing and lymphodepletion regimens of brexucabtagene autoleucel (brexu-cel), tisagenlecleucel (tisa-cel), and obecabtagene autoleucel (obe-cel) differ, with insights into obe-cel’s double infusion approach, as well as a deeper dive into the ZUMA-3 trial’s design and data updates with brexu-cel in relapsed/refractory acute lymphoblastic leukemia (R/R ALL).
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Video content above is prompted by the following:
- Aside from obe-cel’s different design, what are the differences between the dosing and lymphodepletion regimen among brexu-cel, tisa-cel, and obe-cel?
- Please comment on obe-cel’s double infusion approach.
- Please review the ZUMA-3 trial study design and key data updates with brexu-cel.
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