Dr. Pegram on Pertuzumab Plus Trastuzumab and Chemotherapy in Breast Cancer

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Mark D. Pegram, MD, associate director, clinical research, director, Breast Cancer Program, Stanford Cancer Institute, discusses the current treatment landscape for patients with HER2-positive breast cancer.

Mark D. Pegram, MD, associate director, clinical research, director, Breast Cancer Program, Stanford Cancer Institute, discusses the current treatment landscape for patients with HER2-positive breast cancer.

Based on level 1 evidence, there is good data to support the use of pertuzumab (Perjeta) plus trastuzumab (Herceptin) with chemotherapy in the first line setting. This is then followed by T-DM1 in the second line, states Pegram.

This has set the standard of care for the HER2-postive metastatic breast cancer patient population, explains Pegram.

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