Mariana C. Stern, PhD, discusses the biggest gaps identified in the 2026 AACR Cancer Disparities Progress Report and what oncologists can do to combat them.
|Articles|March 9, 2011
- December 2010
- Volume 4
- Issue 12
Effects of UV Radiation Are Cumulative
Author(s)OBTN
An article in Oncogene further explains how ultraviolet (UV) radiation helps transform skin cells into basal cell carcinoma.
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An article in Oncogene further explains how ultraviolet (UV) radiation helps transform skin cells into basal cell carcinoma. Cells exposed to UV radiation ramp up production of protein kinase D, an enzyme that helps cells survive. The effect is cumulative: more exposure causes more protein kinase D expression, increasing the likelihood that DNA damaged skin cells survive and replicate. Pretreating skin cells with antioxidants reduced protein kinase D activation, suggesting that free radicals also contribute to skin cancer development.
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Maurie Markman, MD, discusses conflicts of interest in cancer care.
In an OncLive Peer Exchange, experts discussed the evolving treatment landscape in CLL, spanning frontline selection to emerging next-generation agents.
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