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|Articles|March 9, 2011

Oncology & Biotech News

  • December 2010
  • Volume 4
  • Issue 12

Effects of UV Radiation Are Cumulative

Author(s)OBTN

An article in Oncogene further explains how ultraviolet (UV) radiation helps transform skin cells into basal cell carcinoma.

An article in Oncogene further explains how ultraviolet (UV) radiation helps transform skin cells into basal cell carcinoma. Cells exposed to UV radiation ramp up production of protein kinase D, an enzyme that helps cells survive. The effect is cumulative: more exposure causes more protein kinase D expression, increasing the likelihood that DNA damaged skin cells survive and replicate. Pretreating skin cells with antioxidants reduced protein kinase D activation, suggesting that free radicals also contribute to skin cancer development.

Articles in this issue

almost 15 years ago

Medulloblastoma Subtypes Are Different Diseases

almost 15 years ago

ASH 2010: CPX-351 Improves Response in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia

almost 15 years ago

ASH 2010: Elotuzumab Highly Active in Patients With Advanced Myeloma

almost 15 years ago

ASH 2010: Intensified R-ACVBP More Effective and More Toxic Than R-CHOP in Diffuse Large B-Cell Lymphoma

almost 15 years ago

ASH 2010: Carfilzomib Shrinks Tumors in More Than One-Third of Pretreated Myeloma Patients

almost 15 years ago

ASH 2010: Brentuximab Vedotin Produces High Response Rate in Relapsed or Refractory Hodgkin Lymphoma

almost 15 years ago

ASH 2010: Bosutinib Shows Promise as First-line Treatment of Chronic Myelogenous Leukemia

almost 15 years ago

ASH 2010: Multiple Benefits Observed for Bortezomib in Newly Diagnosed Myeloma Patients

almost 15 years ago

FDA Green-Lights Phase III Trial for Drug-Eluting Microspheres in Liver Cancer

almost 15 years ago

FDA Requests Label Change for Generic Docetaxel

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