
Opinion|Videos|July 24, 2024
Examining the Evolving 3L Treatment Landscape for mCRC
Colorectal cancer specialists examine treatment sequencing strategies for third-line and subsequent therapy settings, while also evaluating regorafenib's efficacy and real-world outcomes.
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Episodes in this series

- Briefly Given the latest approvals, is there a continued role for regorafenib in mCRC and how do real-world outcomes support its use? (Yisilamu P, et al. ASCO 2024. Abstract e15562)
- Dr Marshall to Panel:Let’s explore sequencing strategies for CRC in the 3L setting and beyond. Discuss how new data and other considerations impact treatment selection and sequencing.
- Dr Marshall to Panel: How would you describe your current approach to treatment sequencing?
- Dr Benson: How do you approach treating patients with fruquintinib from FRESCO and FRESCO-2 studies according to prior treatment sequence? (
Bekaii-Saab T, et al. ASCO 2024. Abstract 3579 .)- Impact of prior bevacizumab
- Dr Fakih:Please comment on recently presented data from the SUNLIGHT study and the implications on your treatment sequencing:
- Impact of prior fluoropyrimidine (
Fakih, et al. ASCO GI 2024. Abstract 114 ) - Impact of prior bevacizumab
- Impact of prior fluoropyrimidine (
- Dr Cohen: Regorafenib and/or TAS-102 sequencing (
Signorelli C, et al. ASCO 2024. Abstract e15553)
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