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Opinion|Videos|July 3, 2024

Novel Combination Regimens for 2L mCRC: Insights from ASCO 202

Author(s)John Marshall, MD, Al B. Benson III, MD, FACP, FACCC, FASCO , Kristen Ciombor, MD, MSCI

The panel examines data from the ZL-IRIAN study and Phase II study, which provide insights into second-line treatment options for patients with metastatic colorectal cancer.

Episodes in this series

5 KOLs are featured in this panel.

EP. 1 Overview of Molecular Testing and Barriers in mCRC

5 KOLs are featured in this panel.

EP. 2 Clinical Considerations for 2L Treatment Sequencing in mCRC

5 KOLs are featured in this panel.

EP. 3 Novel Combination Regimens for 2L mCRC: Insights from ASCO 202

5 KOLs are featured in this panel.

EP. 4 Exploring Toxicities for Second Line Treatments in mCRC

5 KOLs are featured in this panel.

EP. 5 Existing Challenges for Patients Receiving 3L+ Therapies in mCRC

5 KOLs are featured in this panel.

EP. 6 Factors Driving 3L Therapeutic Selection for mCRC

5 KOLs are featured in this panel.

EP. 7 Exploring Data Outcomes From the SUNLIGHT Trial

5 KOLs are featured in this panel.

EP. 8 Fruquintinib for mCRC: Data from the FRESCO & FRESCO-2 Studies

5 KOLs are featured in this panel.

EP. 9 Examining the Evolving 3L Treatment Landscape for mCRC

5 KOLs are featured in this panel.

EP. 10 Additional Key Takeaways of ASCO 2024 Data in mCR

5 KOLs are featured in this panel.

EP. 11 Future Outlooks in the Treatment of Metastatic Colorectal Cancer

Dr Cohen:ZL-IRIAN study (NCT05229003; Wang C, et al. ASCO 2024. Abstract 3570)– Irinotecan plus anlotinib ± penpulimab in 2L mCRC
Dr Ciombor: Ph II study (Zhao W, et al. ASCO 2024. Abstract 3571) – fruquintinib plus investigator choice of chemotherapy in 2L mCRC

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