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Opinion|Videos|July 10, 2024

Exploring Toxicities for Second Line Treatments in mCRC

Author(s)John Marshall, MD, Al B. Benson III, MD, FACP, FACCC, FASCO , Kristen Ciombor, MD, MSCI

The panel examines prevalent adverse events experienced by patients receiving second-line biomarker-directed therapy for metastatic colorectal cancer.

Episodes in this series

5 KOLs are featured in this panel.

EP. 1 Overview of Molecular Testing and Barriers in mCRC

5 KOLs are featured in this panel.

EP. 2 Clinical Considerations for 2L Treatment Sequencing in mCRC

5 KOLs are featured in this panel.

EP. 3 Novel Combination Regimens for 2L mCRC: Insights from ASCO 202

5 KOLs are featured in this panel.

EP. 4 Exploring Toxicities for Second Line Treatments in mCRC

5 KOLs are featured in this panel.

EP. 5 Existing Challenges for Patients Receiving 3L+ Therapies in mCRC

5 KOLs are featured in this panel.

EP. 6 Factors Driving 3L Therapeutic Selection for mCRC

5 KOLs are featured in this panel.

EP. 7 Exploring Data Outcomes From the SUNLIGHT Trial

5 KOLs are featured in this panel.

EP. 8 Fruquintinib for mCRC: Data from the FRESCO & FRESCO-2 Studies

5 KOLs are featured in this panel.

EP. 9 Examining the Evolving 3L Treatment Landscape for mCRC

5 KOLs are featured in this panel.

EP. 10 Additional Key Takeaways of ASCO 2024 Data in mCR

5 KOLs are featured in this panel.

EP. 11 Future Outlooks in the Treatment of Metastatic Colorectal Cancer

Briefly discuss common AEs for patients treated with 2L biomarker-directed therapy for mCRC.
- What similarities and differences can be observed based on specific clinically actionable targets?
- What strategies have you explored to mitigate and manage those events?
Dr Marshall: Based on the following data updates presented in mCRC, how does this impact the future treatment landscape in the second line setting?

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