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Opinion|Videos|July 29, 2024

Expert Perspectives in Navigating Treatment Strategies with CDK4/6 Inhibitors in HR+ Breast Cancer

Author(s)Kelly E. McCann, MD, PhD, Sara A. Hurvitz, MD, FACP , Virginia Kaklamani, MD

A panel of experts offer perspectives in navigating treatment strategies with CDK4/6 inhibitors.

Episodes in this series

4 KOLs are featured in this series.

EP. 1 Expert Insights on Biomarker Testing in Early-Stage Breast Cancer

4 KOLs are featured in this series.

EP. 2 Insights from TAILORx and RxPONDER in Guiding Treatment in Early-Stage HR+ Breast Cancer

4 KOLs are featured in this series.

EP. 3 Advancements in Adjuvant Therapy in Early-Stage HR+ Breast Cancer

4 KOLs are featured in this series.

EP. 4 Expert Perspectives on Optimizing Biomarker Testing in Advanced HR+/HER2- Breast Cancer

4 KOLs are featured in this series.

EP. 5 Potential With Individual Tumor Sequencing With Bespoke Testing Methodologies and ctDNA

4 KOLs are featured in this series.

EP. 6 Updates in Treatment Approaches With CDK4/6 Inhibitors in HR+ Breast Cancer

4 KOLs are featured in this series.

EP. 7 Expert Perspectives in Navigating Treatment Strategies with CDK4/6 Inhibitors in HR+ Breast Cancer

4 KOLs are featured in this series.

EP. 8 Navigating 2L Treatment Strategies with Oral SERDs and Elasestrant

4 KOLs are featured in this series.

EP. 9 Treatment Advancements Targeting the PI3K/AKT Pathway in HR+ Breast Cancer

4 KOLs are featured in this series.

EP. 10 ADC-Based Treatment Strategies HR+Breast Cancer:Updates from DESTINY-Breast06

4 KOLs are featured in this series.

EP. 11 Expert Perspectives in Sequencing ADC-Based Therapies in HR+ Breast Cancer

4 KOLs are featured in this series.

EP. 12 Looking Ahead: Expert Future Perspectives in the HR+ Breast Cancer Landscape

Video content above is prompted by the following:

Treatment options post progression on CDK4/6i + ET

What is your overall perception on the class of oral SERDs? How will they continue to impact the treatment landscape?
What are your perceptions on efficacy and safety data? What has your experience been in practice with:
- Elacestrant
  - ASCO 2024 #1071: Real-world (RW) elacestrant use patterns and therapeutic outcomes.
  - ASCO 2024 #1064: Elacestrant plus abemaciclib Preliminary data from ELECTRA
  - ASCO 2024 #1069: Elacestrant in various combinations: Preliminary data from ELEVATE
  - Bardia Cancer Res 2023: GS3-01 EMERALD phase 3 trial of elacestrant vs endocrine therapy: Updated results by duration of prior CDK4/6i in metastatic setting

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