Opinion|Videos|January 6, 2025
Insights Into Ongoing Investigational Studies in Lung LCNEC
Author(s)Martin Dietrich, MD, PhD, Soo-Ryum Yang, MD
Panelists discuss ongoing lung large cell neuroendocrine carcinoma (LCNEC) trials involving both familiar and novel agents, including phase 2 durvalumab + EP (1L), phase 2 LCNEC-ALPINE atezolizumab + EP (1L), phase 1/2 SKYBRIDGE PT217 DLL3/CD47 bispecific antibody (2L+), and phase 1 LB2102 DLL2-directed CAR T (2L+).
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Episodes in this series
- Please briefly describe and provide any thoughts for ongoing lung LCNEC trials, with both familiar and novel agents:
- Phase II durvalumab + EP, 1L
- Phase 2 LCNEC-ALPINE atezolizumab + EP, 1L
- Phase 1/2 SKYBRIDGE PT217 DLL3/CD47 bispecific ab, 2L+
- Phase 1 LB2102 DLL2-directed CAR T, 2L+
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