Opinion|Videos|December 23, 2024
The Role of DLL3 in LCNEC of the Lung
Author(s)Martin Dietrich, MD, PhD, Soo-Ryum Yang, MD
Panelists discuss the typical treatment approach for patients with lung large cell neuroendocrine carcinoma (LCNEC), the patient-specific factors considered in first-line treatment selection, insights from the ASCO 2024 retrospective studies on first-line systemic treatment outcomes, and key considerations for choosing a second-line treatment strategy.
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Episodes in this series
- Given the limited therapeutic options for patients with lung LCNEC, what is your typical treatment approach?
- What patient-specific factors do you consider to guide your first-line treatment selection?
- Please share your thoughts on the ASCO 2024 retrospective studies examining first-line systemic treatment outcomes: 1. (
Nassar et al, ASCO 2024 ); 2. (Matteson et al., ASCO 2024 )- What are your key considerations for choosing a second-line treatment strategy?
- How has the tarlatamab approval in SCLC(
Ahn et al., NEJM 2023 ) impacted your treatment approach for patients with LCNEC?
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