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Opinion|Videos|November 29, 2024

KEYNOTE-361 Highlights: Challenges and Insights

Author(s)Thomas Powles MBBS, MRCP, MD

Thomas Powles, MBBS, MRCP, MD, discusses how the KEYNOTE-361 trial failed because of the trial’s design. Data show that the maintenance phase of the trial is what was driving the benefit and that the longest survival with this trial was 17 months with both pembrolizumab and chemotherapy treatment rather than just chemotherapy.

Episodes in this series

1 expert in this video

EP. 1 Outlining the Current First-Line Treatment Landscape in Metastatic Urothelial Cancer: Starting With a Cisplatin-Ineligible Patient Case

1 expert in this video

EP. 2 Single-Agent Immune Therapy in UC: The Need for More

1 expert in this video

EP. 3 KEYNOTE-361 Highlights: Challenges and Insights

1 expert in this video

EP. 4 Challenges With Avelumab Maintenance in Bladder Cancer and Introduction to ADCs in UC

1 expert in this video

EP. 5 Timeline of Enfortumab Vedotin in UC: From Previously Treated UC to Frontline Therapy

1 expert in this video

EP. 6 Final Clinical Perspectives: EV+P is the New Standard of Care in Frontline Treatment of UC

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