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Opinion|Videos|November 22, 2024

Single-Agent Immune Therapy in UC: The Need for More

Author(s)Thomas Powles MBBS, MRCP, MD

Thomas Powles, MBBS, MRCP, MD, discusses how different trials have been used to study urothelial cancer (UC) treatments, including DANUBE, IMvigor130, and KEYNOTE-361, all of which are frontline, randomized, phase 3 studies that were unsuccessful. A trial that had better results involved nivolumab plus gemcitabine/cisplatin, due to patients being in better physical condition to withstand chemotherapy.

Episodes in this series

1 expert in this video

EP. 1 Outlining the Current First-Line Treatment Landscape in Metastatic Urothelial Cancer: Starting With a Cisplatin-Ineligible Patient Case

1 expert in this video

EP. 2 Single-Agent Immune Therapy in UC: The Need for More

1 expert in this video

EP. 3 KEYNOTE-361 Highlights: Challenges and Insights

1 expert in this video

EP. 4 Challenges With Avelumab Maintenance in Bladder Cancer and Introduction to ADCs in UC

1 expert in this video

EP. 5 Timeline of Enfortumab Vedotin in UC: From Previously Treated UC to Frontline Therapy

1 expert in this video

EP. 6 Final Clinical Perspectives: EV+P is the New Standard of Care in Frontline Treatment of UC

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