Opinion

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MARIPOSA: Clinical Implications

Panelists discuss how the MARIPOSA trial demonstrated strong efficacy with amivantamab plus lazertinib that appears comparable to FLAURA2’s results with osimertinib plus chemotherapy, although cross-trial comparisons should be interpreted cautiously given differences in study populations and the need for mature overall survival data from both trials.

Video content above is prompted by the following:

  • MARIPOSA evaluated amivantamab with lazertinib. How does the progression-free survival and overall response rate data from MARIPOSA compare with the outcomes seen in FLAURA2?

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