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Opinion|Videos|January 5, 2026

Recent Clinical Data in BRAF-Mutated NSCLC

Panelists discuss the latest trial results supporting dual-pathway inhibition in BRAF-mutated metastatic lung cancer.

Panelists review updated survival and response outcomes from recent clinical trials evaluating combination therapy in BRAF-mutated lung cancer. They note that durable responses and consistent safety profiles support the regimen’s continued integration into frontline management.

They emphasize the importance of understanding cross-trial comparisons carefully, as differences in patient populations and follow-up times can affect interpretation. The growing body of evidence reinforces confidence in targeted approaches for this molecularly defined subset.

Overall, they conclude that these findings have established dual inhibition as a validated strategy for BRAF-driven disease, significantly advancing standards of care.

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