Relapsed/Refractory Multiple Myeloma: Preparing Patients for the CAR T-Cell Therapy Journey

Dr. Joshua Richter and Dr. Marco Davila discuss how to prepare patients with relapsed/refractory multiple myeloma (RRMM) for the CAR T-cell therapy process by setting clear expectations before treatment begins. Dr. Davila explains that initial consultations focus on the potential for durable remission while providing a realistic overview of the treatment pathway, including eligibility assessment, insurance authorization, T-cell collection, caregiver requirements, and decisions regarding inpatient or outpatient treatment. He emphasizes the central role of nurse coordinators in guiding patients through each step of the process and coordinating communication across the multidisciplinary care team. The discussion also highlights the importance of collecting T cells as early as feasible to facilitate treatment planning and preserve future options. By combining thorough education with individualized care coordination, the faculty illustrates how comprehensive preparation helps patients and caregivers better understand the logistics, anticipated toxicities, and overall goals of CAR T-cell therapy, enabling informed decision-making and a smoother treatment experience in RRMM.