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Opinion|Videos|January 27, 2025

Second-line Treatment Landscape in Relapsed/Refractory DLBCL

Author(s)David Miklos, MD, Haifaa Abdulhaq, MD, Frederick Locke, MD

A concise discussion of second-line treatment options for DLBCL, focusing on preferred regimens for transplant-eligible and ineligible patients, and tailored approaches based on relapse timing.

Episodes in this series

EP. 1 Emerging Updates in Front-line Treatment Approach of DLBCL

EP. 1 Emerging Updates in Front-line Treatment Approach of DLBCL

EP. 2 Insights from POLARIX: How do Novel Perspectives Influence Treatment Outcomes in DLBCL?

EP. 2 Insights from POLARIX: How do Novel Perspectives Influence Treatment Outcomes in DLBCL?

EP. 3 The Evolving First-line Treatment Approach for DLBCL

EP. 3 The Evolving First-line Treatment Approach for DLBCL

EP. 4 Future Considerations for Front-line Treatment of DLBCL

EP. 4 Future Considerations for Front-line Treatment of DLBCL

EP. 5 Role of Testing in Treatment Decisions - ClonoSeq, PhaseSeq, MRD+Disease

EP. 5 Role of Testing in Treatment Decisions - ClonoSeq, PhaseSeq, MRD+Disease

$EP. 6 Second-line Treatment Landscape in Relapsed/Refractory DLBCL$

EP. 6 Second-line Treatment Landscape in Relapsed/Refractory DLBCL

$EP. 7 The Emerging Role of Second-line CAR T-cell Therapy in Relapsed/Refractory DLBCL$

EP. 7 The Emerging Role of Second-line CAR T-cell Therapy in Relapsed/Refractory DLBCL

$EP. 8 Safety Considerations for Second-line CAR T-cell Therapy in Relapsed/Refractory DLBCL$

EP. 8 Safety Considerations for Second-line CAR T-cell Therapy in Relapsed/Refractory DLBCL

$EP. 9 Real World Perspectives: Outcomes for CAR T-cell Therapy in Relapsed/Refractory DLBCL$

EP. 9 Real World Perspectives: Outcomes for CAR T-cell Therapy in Relapsed/Refractory DLBCL

$EP. 10 Real World Perspectives: Considerations and Challenges for CAR T-cell Therapy in Relapsed/Refractory DLBCL$

EP. 10 Real World Perspectives: Considerations and Challenges for CAR T-cell Therapy in Relapsed/Refractory DLBCL

$EP. 11 Additional Perspectives Beyond CAR T-cell Regimens in Relapsed/Refractory DLBCL.: Bispecifics$

EP. 11 Additional Perspectives Beyond CAR T-cell Regimens in Relapsed/Refractory DLBCL.: Bispecifics

$EP. 12 Academic Insights for the Treatment of Later Relapsed/Refractory DLBCL$

EP. 12 Academic Insights for the Treatment of Later Relapsed/Refractory DLBCL

$EP. 13 Bispecific Antibodies in the Relapsed/Refractory DLBCL Treatment Landscape$

EP. 13 Bispecific Antibodies in the Relapsed/Refractory DLBCL Treatment Landscape

$EP. 14 Future Perspectives for the Treatment of Relapsed/Refractory DLBCL$

EP. 14 Future Perspectives for the Treatment of Relapsed/Refractory DLBCL

Video content above is prompted by the following:

Briefly discuss second-line (2L) treatment of DLBCL.

What are preferred regimens for transplant ineligible versus transplant eligible?
What are preferred regimens for patients that relapse within 12 months versus those that do not progress within 12 months?

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