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News|Videos|March 6, 2025

The Evolving Landscape of mBC Treatment: Unmet Needs and Future Predictions

Author(s)Joyce O’Shaughnessy, MD, Alison Conlin, MD

Episodes in this series

EP. 1 Clinical Perspectives on Biomarker Testing in mBC

EP. 1 Clinical Perspectives on Biomarker Testing in mBC

EP. 2 Repeat Biomarker Testing in mBC: Navigating the Rapidly Evolving Treatment Landscape

EP. 2 Repeat Biomarker Testing in mBC: Navigating the Rapidly Evolving Treatment Landscape

EP. 3 Selecting the Optimal CDK4/6 Regimen for First-Line Therapy

EP. 3 Selecting the Optimal CDK4/6 Regimen for First-Line Therapy

EP. 4 Clinical Considerations for CDK4/6 Inhibition Beyond Progression

EP. 4 Clinical Considerations for CDK4/6 Inhibition Beyond Progression

EP. 5 Expert Insights: Managing Patients with PIK3CA Mutations

EP. 5 Expert Insights: Managing Patients with PIK3CA Mutations

EP. 6 Navigating Treatment Selection in Patients with Both ESR1 and PIK3CA Mutations and Expert Perspective for Integrating Oral SERDs into Clinical Practice

EP. 6 Navigating Treatment Selection in Patients with Both ESR1 and PIK3CA Mutations and Expert Perspective for Integrating Oral SERDs into Clinical Practice

EP. 7 The Emerging Role of Triplet Therapy in mBC: Opportunities and Challenges

EP. 7 The Emerging Role of Triplet Therapy in mBC: Opportunities and Challenges

EP. 8 The Evolving Landscape of mBC Treatment: Unmet Needs and Future Predictions

EP. 8 The Evolving Landscape of mBC Treatment: Unmet Needs and Future Predictions

Video content above is prompted by the following:

Dr. Conlin to Dr. O’Shaughnessy: Looking ahead, how do you see the treatment landscape evolving?
- What impact might the SERENA-6 trial have on sequencing practices (Turner et al. Future Oncology 2023)?
- What mechanisms of resistance to PI3K/AKT pathway inhibitors or oral SERDs do you anticipate?
- What unmet needs remain to be addressed?

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