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Opinion|Videos|February 3, 2025

Treatment Insights for R/M HPV-Positive HNSCC

Author(s)Francis Paul Worden, MD, University of Michigan Comprehensive Cancer Center, Kevin Harrington, MBBS, MRCP, FRCR, FRCP, PhD, DIC

Panelists discuss key research priorities for recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC), which include expanding PDS0101/pembrolizumab trials to identify optimal patient subgroups, addressing resistance mechanisms, and exploring novel biomarkers. Emerging immunotherapy combinations and targeted therapies show promise.

Episodes in this series

2 experts are featured in this series.

EP. 1 Introduction and Incidence of HPV-Positive Head and Neck Cancer

2 experts are featured in this series.

EP. 2 Understanding HPV-Positive HNSCC: Disease Presentation and Risk Factors

2 experts are featured in this series.

EP. 3 Navigating Treatment for HPV-Positive HNSCC Patients

2 experts are featured in this series.

EP. 4 Academic Perspectives for the Management of HPV-Positive HNSCC

2 experts are featured in this series.

EP. 5 Updates From VERSATILE-002: Pembrolizumab Plus PDS0101 (HPV-16–Targeted Cancer Vaccine) in HPV-Positive HNSCC

2 experts are featured in this series.

EP. 6 Emerging Phase 3 Trial: Pembrolizumab Plus PDS0101 (HPV-16 Targeted Cancer Vaccine) in HPV-Positive HNSCC (VERSATILE-003)

2 experts are featured in this series.

EP. 7 Treatment Insights for R/M HPV-Positive HNSCC

2 experts are featured in this series.

EP. 8 Future Considerations for the Treatment of R/M HPV-Positive HNSCC

Video content above is prompted by the following:

What are the most pressing unmet needs related to the treatment of R/M HNSCC?

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