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Understanding HPV-Positive HNSCC: Disease Presentation and Risk Factors

Panelists discuss how, HPV-positive head and neck squamous cell carcinoma (HPV+ HNSCC) typically presents differently from HPV-negative cases. Patients often present with smaller primary tumors but more advanced nodal disease, commonly with cystic lymph node metastases in the neck. The most frequent site is the oropharynx, particularly the tonsils and base of tongue.

Video content above is prompted by the following:

  • Understanding HPV+ HNSCC: Disease Presentation, and Risk Factors
  • How does HPV+ HNSCC typically present in patients, and how severe is the disease compared to HPV- cancers?
  • What are the key risk factors for developing HPV+ HNSCC, and how can they impact prognosis?

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