Opinion|Videos|January 27, 2025
Updates From VERSATILE-002: Pembrolizumab Plus PDS0101 (HPV-16–Targeted Cancer Vaccine) in HPV-Positive HNSCC
Panelists discuss how, PDS0101 uses Versamune® lipid nanoparticles to deliver HPV16 antigens, activating T-cells. Early Phase 2 data with pembrolizumab showed promise in HPV16+ head & neck cancer patients.
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Video content above is prompted by the following:
- Please describe the mechanism of action of the novel Versamune (PDS0101) HPV-16 targeted cancer vaccine.
- Please discuss the recent data presented for the Phase 2 VERSATILE-002 study of PDS0101 + pembrolizumab in adults with HPV16 and PD-L1 positive recurrent/metastatic HNSCC.
- Weiss et al. ESMO 2024
- Versatile-002 - 879P - ESMO 2024
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