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Opinion|Videos|August 2, 2023

Understanding Mechanisms of Action: Ruxolitinib, Ibrutinib, and Belumosudil

Author(s)Preet M. Chaudhary, MD, PhD, Noah Merin, MD, PhD

Dr. Merin describes the mechanisms of action of ruxolitinib, ibrutinib, and belumosudil and shares clinical pearls for community oncologists on methods for achieving response with these agents.

Episodes in this series

EP. 1 The Chronic GvHD Landscape: Risk Factors and Diagnosis

EP. 1 The Chronic GvHD Landscape: Risk Factors and Diagnosis

EP. 2 First-line Treatment for Patients with Chronic GvHD

EP. 2 First-line Treatment for Patients with Chronic GvHD

$EP. 3 Defining and Managing Steroid Refractory Chronic GvHD$

EP. 3 Defining and Managing Steroid Refractory Chronic GvHD

$EP. 4 Role of Ruxolitinib in Steroid-Refractory Chronic GvHD$

EP. 4 Role of Ruxolitinib in Steroid-Refractory Chronic GvHD

EP. 5 Understanding Mechanisms of Action: Ruxolitinib, Ibrutinib, and Belumosudil

EP. 5 Understanding Mechanisms of Action: Ruxolitinib, Ibrutinib, and Belumosudil

$EP. 6 Key Efficacy Data of Ibrutinib and Belumosudil in Steroid-Refractory Chronic GvHD Patients$

EP. 6 Key Efficacy Data of Ibrutinib and Belumosudil in Steroid-Refractory Chronic GvHD Patients

Experts on GVHD

EP. 7 Real World Data on the Use of Ruxolitinib and Treatment Selection in chronic GvHD

Experts on GVHD

EP. 8 Future Directions in Chronic GvHD

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