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Daratumumab Plus Lenalidomide/Dexamethasone Improves PFS in Frontline Myeloma Trial

Jason M. Broderick @jasoncology
Published: Tuesday, Oct 30, 2018

Jan van de Winkel, PhD

Jan van de Winkel, PhD
Adding daratumumab (Darzalex) to lenalidomide (Revlimid) and dexamethasone (DRd) reduced the risk of disease progression or death by 45% compared with lenalidomide/dexamethasone (Rd) alone in newly diagnosed patients with multiple myeloma who are not candidates for high-dose chemotherapy and autologous stem-cell transplant (ASCT).1

The companies noted that additional data from the trial will be submitted for presentation at a medical conference and publication in a peer-reviewed journal. Genmab and Janssen also intend to communicate with regulatory authorities regarding an indication for the triplet regimen in this setting.
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