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Expert Highlights Immunotherapy Potential in Ovarian Cancer

Danielle Bucco
Published: Monday, Sep 18, 2017

Dmitriy Zamarin, MD, PhD

Dmitriy Zamarin, MD, PhD
Immunotherapy has been slower to demonstrate progress in gynecologic cancers than in several other solid tumors, experts say.

on Treatment Options in Ovarian Cancer, Zamarin, a medical oncologist at Memorial Sloan Kettering Cancer Center, discusses immunotherapy for patients with ovarian cancer.

OncLive: Please provide an overview of your presentation on immunotherapy in ovarian cancer.

Zamarin: I discussed the different types of treatments that are used, such as vaccines. I mainly focused on immune checkpoint inhibitors, which is the class of agents that has been in the most advanced clinical development—not just in ovarian cancer, but other cancer types, as well.

What have we seen so far regarding vaccines? 

Cancer vaccines are probably one of the older types of immunotherapy. The interest stems from the success of vaccines in the infectious disease setting. The idea was: can we use this in a therapeutic setting in advanced cancers, or even in some of the precancerous conditions?
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