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FDA Grants Brentuximab Vedotin Breakthrough Designation for Frontline CD30+ PTCL

Jason M. Broderick @jasoncology
Published: Thursday, Nov 15, 2018

Clay Siegall, PhD

Clay Siegall, PhD
The FDA has granted brentuximab vedotin (Adcetris) a breakthrough therapy designation for use in combination with chemotherapy for the frontline treatment of patients with CD30-expressing peripheral T-cell lymphoma (PTCL).

“Data from the ECHELON-2 phase III trial of Adcetris in combination with chemotherapy showed superior progression-free survival and overall survival versus the standard of care chemotherapy regimen, CHOP, in the treatment of frontline CD30-expressing peripheral T-cell lymphomas,” Clay Siegall, PhD, president and chief executive officer of Seattle Genetics, said in a press release.

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