The FDA has granted a breakthrough therapy designation to capmatinib (INC280) as a first-line treatment for patients with MET
exon14 skipping (MET
ex14)—mutated non–small cell lung cancer (NSCLC).1
- Novartis investigational lung cancer therapy capmatinib (INC280) granted FDA Breakthrough Therapy Designation for patients with MET-mutated advanced non-small cell lung cancer[news release]. Basel, Switzerland: Novartis. Published September 6, 2019. https://bit.ly/2lCvaSy. Accessed September 6, 2019.
- Wolf J, Setons T, Han J-Y, et al. Capmatinib (INC280) in METΔex14-mutated advanced non-small cell lung cancer (NSCLC): efficacy data from the phase II GEOMETRY mono-1 study. J Clin Oncol. 2019;37(suppl; abstr 9004). doi: 10.1200/JCO.2019.37.15_suppl.9004.
... to read the full story