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Klopp Comments on Optimizing Chemoradiation in Endometrial Cancer

Danielle Bucco
Published: Tuesday, Mar 20, 2018

Ann H. Klopp, MD, PhD

Ann H. Klopp, MD, PhD
In a debate at the 2018 Society of Gynecologic Oncology Winter Meeting, physicians reviewed the optimal use of adjuvant chemoradiation (CRT) in patients with stage III endometrial cancer, compared with radiotherapy (RT) or chemotherapy (CT) alone.

at the meeting, Klopp, an associate professor of radiation oncology at The University of Texas MD Anderson Cancer Center, discussed optimizing the use of chemoradiation and the future of the treatment landscape in endometrial cancer.

OncLive: Please provide an overview of your presentation on chemotherapy and radiation in endometrial cancer.What is your opinion on the debate?

Klopp: A combination of chemotherapy and radiation is the best treatment. The data that we have to support my opinion is from the trial that compared radiation with chemoradiation. It showed improved outcomes with an improvement in disease-free survival when patients had both chemotherapy and radiation. In addition to having better outcomes overall, the combination also reduces the risk of having a recurrence in the pelvis, which is what radiation is particularly useful for. 
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