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Novel Radiolabeled ADC Could Improve Outcomes in High-Risk AML

Ariela Katz
Published: Monday, Apr 02, 2018

John Pagel, MD, PhD

John Pagel, MD, PhD
Older patients with active, relapsed, or refractory acute myeloid leukemia (AML) have a low survival rate, very poor risk assessments, and limited therapeutic options, with conventional care consisting primarily of salvage chemotherapy. To address this high-risk population, investigators are pretreating these patients with a novel radiolabeled antibody–drug conjugate, Iomab-B, as part of a stem cell transplantation regimen aimed at improving remission and survival outcomes.
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