Register today for a LIVE national broadcast on New Treatment Options for Rare Diseases in the Soft Tissue for March 5th and 6th!

News >

Olaratumab Falls Short in Phase III Soft Tissue Sarcoma Trial

Gina Columbus @ginacolumbusonc
Published: Friday, Jan 18, 2019

Olaratumab (Lartruvo) in combination with doxorubicin missed the phase III ANNOUNCE trial’s primary endpoint of overall survival (OS) and did not confirm a clinical benefit for patients with advanced or metastatic soft tissue sarcoma (STS) compared with standard doxorubicin, according to Eli Lilly and Company, the manufacturer of olaratumab.1 The OS endpoint in the leiomyosarcoma subpopulation was also not met.

“As ANNOUNCE did not confirm clinical benefit, Lilly is working with global regulators to determine the appropriate next steps for Lartruvo,” the company stated in a press release. “While these discussions are ongoing, patients who are currently receiving Lartruvo may, in consultation with their physician, continue their course of therapy if they are receiving clinical benefit.”

For patients who have not previously received olaratumab, Eli Lilly added that the phase III data do not support starting this therapy in patients with STS outside of a clinical trial.
... to read the full story
To Read the Full Story

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Publication Bottom Border
Border Publication