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Rocapuldencel-T Falls Short in mRCC

Jason M. Broderick @jasoncology
Published: Thursday, Apr 19, 2018

An interim analysis revealed that the immunotherapy rocapuldencel-T is unlikely to meet any of the primary endpoints of the phase III ADAPT trial in patients with metastatic renal cell carcinoma (mRCC). Based on the findings, Argos Therapeutics, the manufacturer of the immunotherapy, has ended the trial. 

Figlin R, Nicolette C, Tannir N, et al. Interim analysis of the phase 3 ADAPT trial evaluating rocapuldencel-T (AGS-003), an individualized immunotherapy for the treatment of newly-diagnosed patients with metastatic renal cell carcinoma (mRCC). In: Proceedings from the 2017 ESMO Congress; September 8-12, 2017; Madrid, Spain. Abstract 11370.

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