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Salvage Daratumumab Reaches High ORR in Relapsed Myeloma Following Allogeneic SCT

Virginia Powers, PhD
Published: Tuesday, Apr 02, 2019

Sonja Essmann MD

Sonja Essmann MD

Patients with multiple myeloma who relapsed following allogeneic stem cell transplantation (SCT) and also failed several posttransplant therapies demonstrated a strong response to daratumumab (Darzalex) salvage therapy, according to findings presented at the 2019 European Society for Blood and Marrow Transplantation Annual Meeting.

Further research is needed to investigate the role of daratumumab in combination with immunomodulatory agents or proteasome inhibitors in the second-line setting, the authors concluded in their poster.
Essmann S, von Pein U-M, Klyuchnikov E, et al. Daratumumab as salvage therapy in relapsed/refractory multiple myeloma patients after allogenic stem cell transplantation. Presented at: 2019 European Society for Blood and Marrow Transplantation Annual Meeting; March 24 to 27, 2019; Frankfurt, Germany. Abstract B249.

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