Vol. 17/No. 16 | OncologyLive

Genome Sequencing Is Mapping a Path to Personalized Treatment for Ovarian Cancer

August 17, 2016

Genome sequencing studies have uncovered an array of distinct genomic drivers underlying various ovarian cancer subtypes. If researchers can capitalize on these discoveries, it may offer a path to more individualized and effective treatment options.

Why CRISPR Gene-Editing Technology Is Captivating Research Field

August 17, 2016

Although researchers have been exploring gene editing for more than 40 years, scientists say the CRISPR technology offers game-changing methods for anticancer research as well as a host of other applications.

Models Pave the Way for Improved Outcomes in Medulloblastoma

August 16, 2016

To discover targeted therapies for the more common and severe types of medulloblastoma, a laboratory at Sanford Burnham Prebys Medical Discovery Institute has led efforts to develop genetically engineered mouse models and patient-derived xenografts for studying the molecular basis of the disease.

What Is a Patient Who Refuses Chemotherapy Really Saying?

August 15, 2016

Although chemotherapy has changed dramatically since it was introduced, platinum-containing combinations remain standard in ovarian cancer. Often, the established regimen can be modified for patients who quite justifiably may fear the toxicities of platinum agents.