Vol. 17/No. 4 | OncologyLive

Genomic Complexity Stifles Targeted Advances in Colorectal Cancer

February 16, 2016

Experts in the field assert that the path forward requires a paradigm shift toward integrative analyses that encompass multiple classes of genomic aberrations and consensus classification of CRC based on genomic data to facilitate more effective management of this disease.

Enterprising Approaches

February 15, 2016

Separating hype from hope has often been problematic when developments that may lead to advances in the oncology field enter the public domain. The mapping of the human genome and the ability to characterize mutations associated with cancer have spawned one of those waves of excess promises.

Bringing Epigenetic Therapies From Bench to Bedside

February 15, 2016

Epigenetic therapy has emerged as a novel approach, not necessarily by killing cancer cells, but perhaps by altering the network of chemical changes that affect the DNA/chromatin within cancer cells.

First-in-Class Drug Targets Stem Cells in Gastric Cancer Trial

February 11, 2016

Manish A. Shah, MD, discusses the BRIGHTER trial, which is investigated BBI608 as a second-line treatment for patients with gastric and gastroesophageal junction cancer who already have undergone platinum and fluoropyrimidine-based chemotherapy.