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Opinion|Videos|January 16, 2026

Additional Real-World Time to Next Treatment Outcomes With Elacestrant in ESR1+ Breast Cancer

Author(s)Hope S. Rugo, MD, Seth Wander, MD, PhD

Researchers analyze real-world data on ESR1-mutated breast cancer treatments, revealing promising outcomes and insights for patient care strategies.

Episodes in this series

EP. 1 Treatment Selection Post–CDK4/6 Inhibition in Advanced ER+ Breast Cancer

EP. 1 Treatment Selection Post–CDK4/6 Inhibition in Advanced ER+ Breast Cancer

EP. 2 The Role of Elacestrant in ER+/HER2– Advanced Breast Cancer Harboring ESR1 Mutations

EP. 2 The Role of Elacestrant in ER+/HER2– Advanced Breast Cancer Harboring ESR1 Mutations

2 experts in this video

EP. 3 The Impact of Clinical and Genomic Factors on Real-World Outcomes With Elacestrant in ESR1+ Breast Cancer

2 experts in this video

EP. 4 Additional Real-World Time to Next Treatment Outcomes With Elacestrant in ESR1+ Breast Cancer

2 experts in this video

EP. 5 Ways Oral SERDs and Targeted Therapies Could Continue to Reshape ER+ Breast Cancer Management

2 experts in this video

EP. 6 Persisting Questions in ER+ Breast Cancer in the Second Line and Beyond

Hope S. Rugo, MD, and Seth Wander, MD, PhD, review real-world time to next treatment outcomes associated with elacestrant in ESR1-mutated breast cancer. They discuss how co-mutations and disease biology may affect treatment durability and sequencing decisions. Rugo and Wander emphasize the value of real-world data in complementing clinical trial findings.

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