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Opinion|Videos|October 28, 2024

Adverse Event Management: Strategies for Reducing Diarrhea Risk in Capivasertib Therapy

Author(s)Joyce O’Shaughnessy, MD, Laura Huppert, MD, Heather Moore, Pharm D

Panelists discuss the strategies they employ to manage adverse events in patients starting capivasertib, including minimizing the risk of diarrhea through dietary considerations and patient education, as well as approaches for monitoring and managing rash associated with the treatment and providing education about it.

Episodes in this series

EP. 1 Insights on Biomarker Testing in HR+/HER2- Advanced Breast Cancer

EP. 1 Insights on Biomarker Testing in HR+/HER2- Advanced Breast Cancer

EP. 2 First-Line Treatment Strategies for HR+/HER2- Advanced Breast Cancer

EP. 2 First-Line Treatment Strategies for HR+/HER2- Advanced Breast Cancer

EP. 3 Role of PI3K/AKT/PTEN Pathway in HR+/HER2- Advanced Breast Cancer

EP. 3 Role of PI3K/AKT/PTEN Pathway in HR+/HER2- Advanced Breast Cancer

EP. 4 Overview of the CAPItello-291 Trial

EP. 4 Overview of the CAPItello-291 Trial

EP. 5 Clinical Experience with Capivasertib

EP. 5 Clinical Experience with Capivasertib

EP. 6 Adverse Event Management: Strategies for Reducing Diarrhea Risk in Capivasertib Therapy

EP. 6 Adverse Event Management: Strategies for Reducing Diarrhea Risk in Capivasertib Therapy

EP. 7 Managing Capivasertib Side Effects: Strategies for Educating, Monitoring, and Addressing Rash and Hyperglycemia

EP. 7 Managing Capivasertib Side Effects: Strategies for Educating, Monitoring, and Addressing Rash and Hyperglycemia

EP. 8 Best Practices in Managing Patients on Capivasertib

EP. 8 Best Practices in Managing Patients on Capivasertib

Video content above is prompted by the following:

1. All faculty: When it comes to adverse event management, what steps do you take to minimize the risk of diarrhea in patients starting capivasertib?

Please comment on the study that evaluated the effect of food and acid-reducing agents on capivasertib. C. Miller BJCP 2023
What education do you provide the patient/caregiver about when to call your practice?

2. All faculty: What strategies do you use to monitor and manage rash and provide education about it in patients on capivasertib?

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