Opinion|Videos|April 16, 2025
CAR T in CLL: Data Highlights and Long-Term Outcomes From ASH 2024
Author(s)Caron A. Jacobson, MD, MMSc, Peter Riedell, MD
Experts discuss recent data updates from the TRANSCEND CLL-004 study on the combination of lisocabtagene maraleucel (liso-cel) and ibrutinib, the potential curative role of chimeric antigen receptor T-cell therapy (CAR T) in relapsed/refractory chronic lymphocytic leukemia (R/R CLL), and the future outlook for CAR T in treating R/R CLL.
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Video content above is prompted by the following:
- There were recent data updates on the combination with liso-cel and ibrutinib from the TRANSCEND CLL-004 study at ASH 2024. Dr Ridell, what were some of the data highlights, and has this data influenced your clinical practice?
- In your clinical expertise, is CAR T potentially curative in R/R CLL?
- In your opinion, what does the future look like for CAR T in R/R CLL?
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