Digital Monitoring and Community Transitions: Hospital-at-Home, Outpatient Step-Up, and Shared Care Models

This segment explores how digital monitoring tools and evolving care models can support the safe administration of bispecific antibody therapies across academic and community settings. Faculty discuss “hospital-at-home” approaches in which patients receive outpatient step-up dosing while being remotely monitored using digital tools such as connected blood pressure cuffs, thermometers, and other vital sign monitoring devices, supported by continuous nursing oversight and emergency response protocols.

The panel also contrasts these approaches with simpler monitoring strategies used in some settings, including home monitoring devices and clear, preemptive instructions for patients and caregivers regarding symptom recognition and early intervention.

The discussion then turns to transitions back to community clinics, including when these transitions are initiated, how long patients remain under the supervision of academic centers, and how virtual follow-up may support ongoing care. Faculty highlight the importance of shared care protocols addressing infection prophylaxis, toxicity monitoring, and dose modifications. Overall, the segment examines how digital monitoring and coordinated referral pathways may support broader and safer use of T-cell–redirecting therapies in community practice.