Opinion|Videos|January 22, 2025
Efficacy and Potential of Revumenib in KMT2A-Translocated Leukemia
Panelists discuss the data updates from the AUGMENT-101 trial, the potential of revumenib to reshape the treatment landscape for patients with heavily pretreated KMT2A-rearranged acute leukemia, including its observed objective response rate (ORR) and complete remission (CR)/ CR with partial recovery of peripheral blood counts (CRh) rate, and the clinical implications of revumenib in the context of bridging to stem cell transplantation.
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Video content above is prompted by the following:
- Briefly comment on data updates presented for the AUGMENT-101 trial.
- Given the 64% ORR and 23% CR/CRh rate observed with revumenib in patients with heavily preated pretreated KMT2A-rearranged acute leukemia patients, how do you see this therapy reshaping the treatment landscape for this high-risk population?
- Briefly comment on the clinical implications, particularly in the context of bridging to stem cell transplantation.?
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