Opinion|Videos|February 26, 2025
Emerging Frontline, Adjuvant, and Neoadjuvant Strategies with T-DXd in HER2+ Breast Cancer
Panelists discuss how emerging data from trials such as DESTINY-Breast09, which is evaluating first-line trastuzumab deruxtecan (T-DXd) with or without pertuzumab, could potentially reshape the treatment paradigm for HER2+ metastatic breast cancer (mBC) by establishing new standards for initial therapy and optimal combination approaches.
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Briefly comment on other novel strategies currently under investigation in HER2+ metastatic breast cancer and discuss their potential impact on future management in this patient population.
• Dr Hurvitz: DESTINY-Breast09 – 1L T-DXd ± pertuzumab in HER2+ mBC
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