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Opinion|Videos|March 6, 2025

Expert Insights on the LAURA Trial: Osimertinib After CRT in Unresectable Stage III EGFRm NSCLC as a New Standard of Care

The discussion focuses on the LAURA trial, which demonstrated that osimertinib significantly improved progression-free survival in patients with EGFR-mutated (EGFRm) locally advanced non–small cell lung cancer (NSCLC) after chemoradiotherapy (CRT), establishing it as a new standard of care with manageable safety concerns.

Episodes in this series

EP. 1 Defining Resectability in Stage III NSCLC: Addressing Key Controversies

EP. 1 Defining Resectability in Stage III NSCLC: Addressing Key Controversies

EP. 2 Multidisciplinary Strategies for Optimizing Care in Unresectable Stage III NSCLC

EP. 2 Multidisciplinary Strategies for Optimizing Care in Unresectable Stage III NSCLC

EP. 3 Optimizing Biomarker Testing for Unresectable Stage III NSCLC

EP. 3 Optimizing Biomarker Testing for Unresectable Stage III NSCLC

EP. 4 Overcoming Barriers to Biomarker Testing in Unresectable NSCLC: Strategies for Improved Access and Implementation

EP. 4 Overcoming Barriers to Biomarker Testing in Unresectable NSCLC: Strategies for Improved Access and Implementation

EP. 5 Tailoring Chemoradiotherapy Approaches in Unresectable Stage III NSCLC

EP. 5 Tailoring Chemoradiotherapy Approaches in Unresectable Stage III NSCLC

EP. 6 Consolidation Durvalumab in Unresectable Stage III NSCLC: Management Strategies and the Role of ctDNA

EP. 6 Consolidation Durvalumab in Unresectable Stage III NSCLC: Management Strategies and the Role of ctDNA

EP. 7 Assessment and Management Strategies for Pneumonitis in Durvalumab Consolidation Post Chemoradiotherapy

EP. 7 Assessment and Management Strategies for Pneumonitis in Durvalumab Consolidation Post Chemoradiotherapy

EP. 8 Exploring the Role of SBRT in Unresectable NSCLC: Patient Selection and Trial Insights

EP. 8 Exploring the Role of SBRT in Unresectable NSCLC: Patient Selection and Trial Insights

EP. 9 A 76-Year-Old Woman With Locally Advanced Unresectable Stage III EGFRm NSCLC

EP. 9 A 76-Year-Old Woman With Locally Advanced Unresectable Stage III EGFRm NSCLC

EP. 10 Expert Insights on the LAURA Trial: Osimertinib After CRT in Unresectable Stage III EGFRm NSCLC as a New Standard of Care

EP. 10 Expert Insights on the LAURA Trial: Osimertinib After CRT in Unresectable Stage III EGFRm NSCLC as a New Standard of Care

EP. 11 Key Takeaways From the PACIFIC-2 Trial: The Role of Concurrent Immunotherapy With CRT

EP. 11 Key Takeaways From the PACIFIC-2 Trial: The Role of Concurrent Immunotherapy With CRT

EP. 12 Closing Thoughts and Clinical Pearls: Future Perspectives in NSCLC

EP. 12 Closing Thoughts and Clinical Pearls: Future Perspectives in NSCLC

Video content above is prompted by the following:

Please provide some background on the LAURA trial evaluating osimertinib after definitive CRT in unresectable stage III EGFRm NSCLC

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